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Smoke Shops in Florence, SC

22 smoke shops in and around Florence, South Carolina.

Florence has about 40,923 residents, which works out to 54 smoke shops per 100,000 people. Population: U.S. Census Bureau, 2024 estimate.

Top 10 smoke shops in Florence

Ranked by how complete and owner-verified the listing info is — hours, phone, website, services. No pay-to-play.

  1. 1coastal vapor

    2405 2nd Loop Rd, Florence, SC 29501

    Vape
    Call Website Directions

  2. 2vaping masters

    1741 S Irby St, Florence, SC 29505

    Vape
    Call Website Directions

  3. 3Palmetto Discount Tobacco

    707 S Parker Dr, Florence, SC 29501-6062

    Discount
    Call Website Directions

  4. 4Smok O Vape

    2112 S Irby St, Florence, SC 29505

    Vape
    Call Directions

  5. 5Ziz Tobacco & Vape

    1555 W Palmetto St, Florence, SC 29501

    Vape
    Call Directions

  6. 7Vape Right

    205 2nd Loop Rd, Florence, SC 29505-2847

    Vape
    Call Directions

  7. 8High End Vape and Tobacco

    1945 W Palmetto St #113, Florence, SC 29501

    Vape
    Call Directions

  8. 9Smoker's Town

    205 2nd Loop Rd, Florence, SC 29505

    Call Directions

  9. 10Smokers Town Third Loop

    202 3rd Loop Rd Ste J & K, Florence, SC 29505

    Call Directions
22smoke shops
54per 100,000 residents
21with a phone
3with a website

Of the 22 smoke shops listed in Florence, 21 give a phone number and 3 have a website. No national chains here — every smoke shop on this page is independent. By what they offer: 12 sell vapes, 2 are discount shops. The nearest bigger selection is Columbia with 55.

Smoke Shops in Florence by feature

Florence 22 smoke shops

All 12 other smoke shops in Florence

By ZIP code: 29501 (5) · 29505 (6) · 29506 (1)

ZIP 29501 5

  1. Tobacco Market

    1733 W Lucas St, Florence, SC 29501

    Call Directions

  2. William and Taylor General Store

    523 W Palmetto St, Florence, SC 29501

    Call Directions

  3. Ziz Tobacco & Vape

    1902 W Lucas St, Florence, SC 29501-1232

    Vape
    Call Directions

  4. Juiced - Vape & Bar

    1001 S Cashua Dr, Florence, SC 29501-6371

    Vape
    Call Directions

  5. Carolina Discount Tobacco

    1733 W Lucas St, Florence, SC 29501-1227

    Discount
    Call Directions

ZIP 29505 6

  1. Vape right

    1739 S Irby St, Florence, SC 29505

    Vape
    Call Directions

  2. Tobacco House

    202 3rd Loop Rd, Florence, SC 29505

    Call Directions

  3. Tobacco Market

    1593 S Irby St, Florence, SC 29505

    Call Directions

  4. Big A’s Smoke Shop

    202 3rd Loop Rd, Florence, SC 29505-3722

    Call Directions

  5. Florence Tobacco And Vape

    2108 S Irby St, Florence, SC 29505-3445

    Vape
    Call Directions

  6. Second Loop Inc

    205 2nd Loop Rd Ste C, Florence, SC 29505-2847

    Directions

ZIP 29506 1

  1. Tobacco & Vape

    3208 E Palmetto St Ste C, Florence, SC 29506-3854

    Vape
    Call Directions

South Carolina statewide, by feature

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